Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Josep Baselga (1959-2021).

Castel, Pau; Toska, Eneda.

Cell ; 184(13): 3349-3351, 2021 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-34171315

2.

Cholesterol is required for transcriptional repression by BASP1.

Loats, Amy E; Carrera, Samantha; Fleming, Anna F; Roberts, Abigail R E; Sherrard, Alice; Toska, Eneda; Moorhouse, Alexander J; Medler, Kathryn F; Roberts, Stefan G E.

Proc Natl Acad Sci U S A ; 118(29)2021 07 20.

Artigo em Inglês | MEDLINE | ID: mdl-34266955

3.

UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.

Wolfe, Andrew L; Zhou, Qingwen; Toska, Eneda; Galeas, Jacqueline; Ku, Angel A; Koche, Richard P; Bandyopadhyay, Sourav; Scaltriti, Maurizio; Lebrilla, Carlito B; McCormick, Frank; Kim, Sung Eun.

Proc Natl Acad Sci U S A ; 118(31)2021 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-34330832

4.

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer.

Glaviano, Antonino; Foo, Aaron S C; Lam, Hiu Y; Yap, Kenneth C H; Jacot, William; Jones, Robert H; Eng, Huiyan; Nair, Madhumathy G; Makvandi, Pooyan; Geoerger, Birgit; Kulke, Matthew H; Baird, Richard D; Prabhu, Jyothi S; Carbone, Daniela; Pecoraro, Camilla; Teh, Daniel B L; Sethi, Gautam; Cavalieri, Vincenzo; Lin, Kevin H; Javidi-Sharifi, Nathalie R; Toska, Eneda; Davids, Matthew S; Brown, Jennifer R; Diana, Patrizia; Stebbing, Justin; Fruman, David A; Kumar, Alan P.

Mol Cancer ; 22(1): 138, 2023 08 18.

Artigo em Inglês | MEDLINE | ID: mdl-37596643

5.

TRI_tool: a web-tool for prediction of protein-protein interactions in human transcriptional regulation.

Perovic, Vladimir; Sumonja, Neven; Gemovic, Branislava; Toska, Eneda; Roberts, Stefan G; Veljkovic, Nevena.

Bioinformatics ; 33(2): 289-291, 2017 01 15.

Artigo em Inglês | MEDLINE | ID: mdl-27605104

6.

WT1 regulates the development of the posterior taste field.

Gao, Yankun; Toska, Eneda; Denmon, Dane; Roberts, Stefan G E; Medler, Kathryn F.

Development ; 141(11): 2271-8, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24803588

7.

Presenilin influences glycogen synthase kinase-3 ß (GSK-3ß) for kinesin-1 and dynein function during axonal transport.

Dolma, Kunsang; Iacobucci, Gary J; Hong Zheng, Kan; Shandilya, Jayasha; Toska, Eneda; White, Joseph A; Spina, Elizabeth; Gunawardena, Shermali.

Hum Mol Genet ; 23(5): 1121-33, 2014 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-24105467

8.

Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation.

Busch, Maike; Schwindt, Heinrich; Brandt, Artur; Beier, Manfred; Görldt, Nicole; Romaniuk, Paul; Toska, Eneda; Roberts, Stefan; Royer, Hans-Dieter; Royer-Pokora, Brigitte.

Hum Mol Genet ; 23(15): 3958-74, 2014 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-24619359

9.

Mechanisms of transcriptional regulation by WT1 (Wilms' tumour 1).

Toska, Eneda; Roberts, Stefan G E.

Biochem J ; 461(1): 15-32, 2014 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-24927120

10.

Epigenetic mechanisms of cancer progression and therapy resistance in estrogen-receptor (ER+) breast cancer.

Toska, Eneda.

Biochim Biophys Acta Rev Cancer ; 1879(3): 189097, 2024 Mar 20.

Artigo em Inglês | MEDLINE | ID: mdl-38518961

11.

ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma.

Jagirdar, Kasturee; Portuallo, Marie E; Wei, Meihan; Wilhide, Matthew; Bravo Narula, Jeremy A; Robertson, Bailey M; Alicea, Gretchen M; Aguh, Crystal; Xiao, Min; Godok, Tetiana; Fingerman, Dylan; Brown, Gregory Schuyler; Herlyn, Meenhard; Elad, Vissy M; Guo, Xinyu; Toska, Eneda; Zabransky, Daniel J; Wubbenhorst, Bradley; Nathanson, Katherine L; Kwatra, Shawn; Goyal, Yogesh; Ji, Hongkai; Liu, Qin; Rebecca, Vito W.

Oncogene ; 43(6): 395-405, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38066089

12.

Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer.

Blawski, Ryan; Vokshi, Bujamin H; Guo, Xinyu; Kittane, Srushti; Sallaku, Mirna; Chen, Wanlu; Gjyzari, Martina; Cheung, Tony; Zhang, Yuhan; Simpkins, Christopher; Zhou, Weiqiang; Kulick, Amanda; Zhao, Peihua; Wei, Meihan; Shivashankar, Pranavkrishna; Prioleau, Tatiana; Razavi, Pedram; Koche, Richard; Rebecca, Vito W; de Stanchina, Elisa; Castel, Pau; Chan, Ho Man; Scaltriti, Maurizio; Cocco, Emiliano; Ji, Hongkai; Luo, Minkui; Toska, Eneda.

Cell Rep ; 43(5): 114174, 2024 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-38700982

13.

ERK Hyperactivation Serves as a Unified Mechanism of Escape in Intrinsic and Acquired CDK4/6 Inhibitor Resistance in Acral Lentiginous Melanoma.

Rebecca, Vito; Jagirdar, Kasturee; Portuallo, Marie; Wei, Meihan; Wilhide, Matthew; Bravo, Jeremy; Robertson, Bailey; Alicea, Gretchen; Aguh, Crsytal; Xiao, Min; Godok, Tetiana; Fingerman, Dylan; Brown, Gregory; Herlyn, Meenhard; Guo, Brian; Toska, Eneda; Zabransky, Daniel; Wubbenhorst, Bradley; Nathanson, Katherine; Kwatra, Shawn; Goyal, Yogesh; Ji, Hongkai; Liu, Qin.

Res Sq ; 2023 Apr 20.

Artigo em Inglês | MEDLINE | ID: mdl-37131684

14.

Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer.

Bianchi, Anna; De Castro Silva, Iago; Deshpande, Nilesh U; Singh, Samara; Mehra, Siddharth; Garrido, Vanessa T; Guo, Xinyu; Nivelo, Luis A; Kolonias, Despina S; Saigh, Shannon J; Wieder, Eric; Rafie, Christine I; Dosch, Austin R; Zhou, Zhiqun; Umland, Oliver; Amirian, Haleh; Ogobuiro, Ifeanyichukwu C; Zhang, Jian; Ban, Yuguang; Shiau, Carina; Nagathihalli, Nagaraj S; Montgomery, Elizabeth A; Hwang, William L; Brambilla, Roberta; Komanduri, Krishna; Villarino, Alejandro V; Toska, Eneda; Stanger, Ben Z; Gabrilovich, Dmitry I; Merchant, Nipun B; Datta, Jashodeep.

Cancer Discov ; 13(6): 1428-1453, 2023 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-36946782

15.

WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line.

Goodfellow, Sarah J; Rebello, Michelle R; Toska, Eneda; Zeef, Leo A H; Rudd, Sean G; Medler, Kathryn F; Roberts, Stefan G E.

Biochem J ; 435(1): 113-25, 2011 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-21269271

16.

A Unique FOXA1-Associated Chromatin State Dictates Therapeutic Resistance in Lobular Breast Cancer.

Blawski, Ryan; Toska, Eneda.

Cancer Res ; 82(20): 3668-3670, 2022 10 17.

Artigo em Inglês | MEDLINE | ID: mdl-36245246

17.

Epigenetic Mechanisms Influencing Therapeutic Response in Breast Cancer.

Arruabarrena-Aristorena, Amaia; Toska, Eneda.

Front Oncol ; 12: 924808, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35774123

18.

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation.

Ladewig, Erik; Michelini, Flavia; Jhaveri, Komal; Castel, Pau; Carmona, Javier; Fairchild, Lauren; Zuniga, Adler G; Arruabarrena-Aristorena, Amaia; Cocco, Emiliano; Blawski, Ryan; Kittane, Srushti; Zhang, Yuhan; Sallaku, Mirna; Baldino, Laura; Hristidis, Vasilis; Chandarlapaty, Sarat; Abdel-Wahab, Omar; Leslie, Christina; Scaltriti, Maurizio; Toska, Eneda.

Cancer Res ; 82(12): 2269-2280, 2022 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-35442400

19.

FOXA1 mutations influence the therapeutic response of breast cancer by altering chromatin state.

Arruabarrena-Aristorena, Amaia; Toska, Eneda.

Mol Cell Oncol ; 8(3): 1891831, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34027035

20.

The present and future of PI3K inhibitors for cancer therapy.

Castel, Pau; Toska, Eneda; Engelman, Jeffrey A; Scaltriti, Maurizio.

Nat Cancer ; 2(6): 587-597, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-35118422

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